Fish Cell Line Acute Toxicity - OECD 249

Effect testing with fish cell lines instead of fish testing…

In times of growing awareness for animal welfare and sustainability, the need for animal-free testing in ecotoxicology is pursued by industry, authorities and customers.
The fish cell line assay with The RTgill-W1 cells (OECD 249) represents an attractive alternative for acute fish toxicity tests (OECD 203). Even though the test is not part of REACH and other legislation documents yet, an increasing amount of data is being generated comparing fish cell line and fish acute toxicity results. The comparability is promising, depending on the respective substance class. Therefore, we are happy to offer OECD 249 tests under GLP.

… with high quality cells
Our in-house cell housekeeping guarantees close monitoring and healthy organisms for reliable testing.

…including up-to-date analytical services
We offer in-house state-of-the-art highly sensitive accompanying chemical analytics using GC-MS, LC-MS/MS or LC-QTOF. With more than 30 years of experience, we can analyze a wide range of substances and degradation products. All chemical methods are fully validated following the most recent guidelines and specifications of regulatory authorities (SANCO/3029/99 rev. 4, SANCO/3030/99 rev. 4).

You matter.
All our studies are conducted under GLP and supported by a broad range of experience in scientific work on a large variety of substances such as chemicals, plant protection products or fragrances and flavours. We strive for complete transparency and a close communication during the course of your studies. Monthly status updates, guaranteed testing slots and real-time updates are only some examples of our customer service.

Interested? Your direct contact person:


Anika Dreier
tel: +49 5066 7067-11